CIRCSORBS1 REGULATES MYOCARDIAL REGENERATION AND REDUCES CANCER THERAPY-RELATED CARDIOVASCULAR TOXICITY THROUGH THE MIR-99/GATA4 PATHWAY

CircSorbs1 regulates myocardial regeneration and reduces cancer therapy-related cardiovascular toxicity through the Mir-99/GATA4 pathway

Abstract Due to the cancer therapy-related cardiovascular toxicity, heart failure following cancer therapy has a significant mortality rate.Gene-targeted therapy promotes the re-entry of existing cardiomyocytes into the cell cycle to achieve myocardial regeneration, which is a promising strategy for preventing and treating heart failure after myoca

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The role of Interleukin-22 in severe acute pancreatitis

Abstract Severe acute pancreatitis (SAP) begins with premature activation of enzymes, promoted by the immune system, triggering a potential systemic inflammatory response that leads to organ failure with increased mortality and a bleak prognosis.Interleukin-22 (IL-22) is a cytokine that may have a Waste Pickup significant role in SAP.IL-22, a membe

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